About Domainex

An Integrated Drug Discovery CRO

Domainex is a multi-award winning, integrated drug discovery CRO and has been setting the highest standards in drug discovery, with a particular emphasis on small molecule research, since 2001. We work in partnership with clients from a variety of sectors including academic, pharmaceutical, biotechnology and patient foundation organisations around the world.

Proven Track Record of Success

We offer you tailored services for every step of the drug discovery process, from expression of recombinant proteins and screening against disease targets to identify hit compounds, through the design and medicinal chemistry optimisation of hits and leads, to take these all the way to your pre-clinical drug candidates. Our multidisciplinary team of scientists works closely with you to generate innovative ideas, and to deliver high-quality results and outputs (e.g. crystallography-grade proteins and novel compounds that meet the desired target product profile), whilst at all times upholding the very highest standards of confidentiality. We have established a strong reputation with a very high level of repeat business and a proven record of success, some of which we can illustrate through the publications and case studies our clients have allowed us to put in the public domain. In 2022, >95% of our clients said they would recommend us to someone in their network. We have also received several awards recognising our customer focus and innovative approach to drug discovery.

A tailored solution for your project

We invite you to find out more about our capabilities, to get to know us and to talk to us about your requirements. We will provide you with comprehensive proposals for your consideration within a short time frame. 

We look forward to hearing from you.

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Our Vision

To be the pre-eminent partner for innovative drug discovery services that improve the quality of life for people living with disease.

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Mission

We will provide outstanding drug discovery services by deploying cutting edge technologies, building lasting relationships and continually advancing our offering.

We know that we are strongest when we work as an integrated team, and towards those ends we foster a highly collaborative, diverse company culture centred on teamwork and continual learning.

Our operations will be underpinned by innovation and passion for high quality science, while respecting wider environmental, social and governance responsibilities.

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Innovative and Customised Services

We integrate seamlessly our innovative and customised biology and chemistry services to advance your disease research projects in a timely and efficient way. Our experience spans a broad range of therapeutic areas, including oncology, inflammation, respiratory and cardiovascular diseases. We have expertise across a wide range of drug target classes, including protein-protein interactions, epigenetic targets (e.g. lysine methyltransferases), a wide range of enzymes (including kinases and proteases),ion channels, and G-protein coupled receptors (GPCRs). Whatever the research phase of your project, we have an unrivalled track record of solving complex challenges.

In addition to our small-molecule drug discovery expertise, we also support clients in other industries, such as biologics, agrochemicals and materials science.

Highly Qualified and Experienced Scientists

Ultimately what determines the success of your project are our scientists – who become committed members of your team, and an extension of your own resources. Our multi-disciplinary team of ~ 100 scientists has a wealth of experience in drug discovery – on average over 10 years per scientist. About 75% of our scientists are PhD qualified and most have previous experience gained from a variety of pharmaceutical and biotechnology companies as well as from leading academic institutes.

Meet some of our highly-experienced scientists

I really enjoy the wide variety of scientific projects, and the range of clients and consultants that I have the pleasure of sharing expertise with.  I’ve had the pleasure of seeing Domainex grow, and retain the friendly, team-working atmosphere that is required to make a successful multidisciplinary research services provider.

Philip Fallon
Joined Domainex in 2007

For me having a varied role is a definite plus. I like the cohesive nature of the company. Everyone is very friendly and it’s easy to interact with people across departments. The wide variation in project work keeps things interesting too!

Mark Stewart
Joined Domainex in 2004

At Domainex both the science and the colleagues are top notch. It’s a very friendly environment with a large variety of projects and opportunities. There is something for everyone.

Gabi Negoita-Giras
Joined Domainex in 2011

At Domainex I enjoy the variety of projects that we come across and working with great people across the disciplines.

Anna Hopkins
Joined Domainex in 2013

I like working at Domainex because the atmosphere is friendly and personal, and the projects are interesting. Every day brings a new challenge.

Steffi Reich
Joined Domainex in 2006

Domainex has that close ‘family’ feel to it which I don’t think is replicated in many other organisations. The feeling of turning up to work knowing you’ll be working with really good, friendly people has really motivated me to stay with the company. I also really enjoy the variety of different projects, which means I am always learning something new and keeps the job interesting and fulfilling.

Jon Powell
Joined Domainex in 2008